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Ann B Moser Selected Research

Adrenoleukodystrophy (Adrenoleukodystrophy, X-Linked)

10/2021Drug discovery for X-linked adrenoleukodystrophy: An unbiased screen for compounds that lower very long-chain fatty acids.
2/2020X-linked adrenoleukodystrophy: Pathology, pathophysiology, diagnostic testing, newborn screening and therapies.
1/2020The peroxisomal fatty acid transporter ABCD1/PMP-4 is required in the C. elegans hypodermis for axonal maintenance: A worm model for adrenoleukodystrophy.
11/2019X-linked Adrenoleukodystrophy: Pathology, Pathophysiology, Diagnostic Testing, Newborn Screening, and Therapies.
10/2019Biomarker Identification, Safety, and Efficacy of High-Dose Antioxidants for Adrenomyeloneuropathy: a Phase II Pilot Study.
10/2018Newborn Screening and Emerging Therapies for X-Linked Adrenoleukodystrophy.
11/2017X-linked adrenoleukodystrophy in a chimpanzee due to an ABCD1 mutation reported in multiple unrelated humans.
6/2017Therapeutic strategies in adrenoleukodystrophy.
1/2017Antioxidant Capacity and Superoxide Dismutase Activity in Adrenoleukodystrophy.
12/2016Newborn Screening for X-Linked Adrenoleukodystrophy.
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Ann B Moser Research Topics

Disease

25Adrenoleukodystrophy (Adrenoleukodystrophy, X-Linked)
10/2021 - 08/2002
6Demyelinating Diseases (Demyelinating Disease)
01/2016 - 12/2005
4Peroxisomal Disorders (Peroxisomal Disorder)
01/2016 - 07/2009
3Neoplasms (Cancer)
05/2021 - 11/2014
3Inflammation (Inflammations)
10/2019 - 08/2002
3Zellweger Syndrome (Zellweger's Syndrome)
10/2018 - 09/2013
3Alzheimer Disease (Alzheimer's Disease)
01/2018 - 06/2011
2Disease Progression
10/2019 - 07/2005
2Inborn Genetic Diseases (Disease, Hereditary)
11/2017 - 09/2007
2Adrenal Insufficiency (Adrenal Gland Hypofunction)
12/2016 - 04/2005
2Prostatic Neoplasms (Prostate Cancer)
02/2015 - 12/2014
2Hypoxia (Hypoxemia)
11/2014 - 11/2008
1Glioblastoma (Glioblastoma Multiforme)
05/2021
1Glioma (Gliomas)
05/2021
1Bipolar Disorder (Manic Depressive Psychosis)
12/2016
1Rhizomelic Chondrodysplasia Punctata
02/2015
1Liver Diseases (Liver Disease)
01/2015
1Hypoglycemia (Reactive Hypoglycemia)
01/2013
1Hyperammonemia
01/2013
1Glutaric Acidemia I
09/2011
1Cataract (Cataracts)
06/2011
1Retinitis Pigmentosa (Pigmentary Retinopathy)
10/2010
1Cerebellar Ataxia (Dysmetria)
10/2010
1Polyneuropathies (Polyneuropathy)
10/2010
1Infections
04/2010
1Vomiting
04/2010
1Gastroenteritis
04/2010
1Dyslipidemias (Dyslipidemia)
11/2008
1Atherosclerosis
11/2008
1Diabetes Mellitus
06/2008
1Peroxisome biogenesis disorders
09/2006

Drug/Important Bio-Agent (IBA)

18Fatty Acids (Saturated Fatty Acids)IBA
10/2021 - 08/2002
7EnzymesIBA
05/2021 - 06/2002
5LipidsIBA
11/2017 - 03/2007
4Phospholipids (Phosphatides)FDA LinkGeneric
05/2021 - 06/2008
3Pharmaceutical PreparationsIBA
10/2021 - 01/2012
3Choline (Choline Chloride)IBA
01/2018 - 09/2006
3Lorenzo's oilIBA
01/2016 - 07/2005
3Phytanic AcidIBA
02/2015 - 10/2010
3Lysophosphatidylcholines (Lysophosphatidylcholine)IBA
01/2015 - 06/2008
2long-chain-fatty-acid-CoA ligaseIBA
05/2021 - 05/2003
2AntioxidantsIBA
10/2019 - 01/2017
2Biomarkers (Surrogate Marker)IBA
10/2019 - 10/2018
2DNA (Deoxyribonucleic Acid)IBA
11/2017 - 02/2003
2PlasmalogensIBA
02/2015 - 06/2011
2AcidsIBA
01/2015 - 12/2014
2Amino AcidsFDA Link
09/2011 - 06/2008
2Messenger RNA (mRNA)IBA
11/2008 - 02/2003
1SphingolipidsIBA
05/2021
1Member 1 Subfamily D ATP Binding Cassette TransporterIBA
01/2020
1Carrier Proteins (Binding Protein)IBA
06/2017
1Superoxide DismutaseIBA
01/2017
1Docosahexaenoic AcidsIBA
12/2016
1Tight Junction ProteinsIBA
11/2015
1alpha-methylacyl-CoA racemaseIBA
02/2015
1pristanic acidIBA
12/2014
1Coenzyme A (CoA)IBA
12/2014
1beta Carotene (Betacarotene)FDA Link
12/2014
1Racemases and Epimerases (Epimerases and Racemases)IBA
12/2014
1alpha-TocopherolFDA Link
12/2014
1Oxygen (Dioxygen)IBA
11/2014
1Lysergic Acid Diethylamide (LSD)IBA
02/2014
1GlycosphingolipidsIBA
02/2014
1Psychosine (Galactosylsphingosine)IBA
02/2014
1GlycolipidsIBA
09/2013
1Acyl Coenzyme A (Acyl CoA)IBA
01/2013
1Urea (Carbamide)FDA LinkGeneric
01/2013
1Acetyl Coenzyme A (Acetyl-CoA)IBA
01/2013
1Glutamic Acid (Glutamate)FDA Link
01/2013
1Carnitine (L-Carnitine)FDA LinkGeneric
03/2012
1BezafibrateIBA
01/2012
1Arginine (L-Arginine)FDA Link
09/2011
1glutaryl-coenzyme A (glutaryl-CoA)IBA
09/2011
1Lysine (L-Lysine)FDA Link
09/2011
1SolutionsIBA
04/2010
1We 201IBA
07/2009
1Antisense OligonucleotidesIBA
11/2008
1CholesterolIBA
11/2008
1Oxyhemoglobins (Oxyhemoglobin)IBA
11/2008
1Lipoproteins (Lipoprotein)IBA
11/2008
1LDL CholesterolIBA
11/2008
1Triglycerides (Triacylglycerol)IBA
11/2008
1VLDL CholesterolIBA
11/2008
1stearoyl-coenzyme A (stearoyl-CoA)IBA
11/2008
1OrnithineIBA
06/2008
1human ABCD1 proteinIBA
06/2008
1Calcineurin InhibitorsIBA
06/2008
1hexacosanoic acidIBA
09/2006
1ChemokinesIBA
12/2005
1CytokinesIBA
12/2005
1trierucateIBA
07/2005
1Adenosine Triphosphate (ATP)IBA
05/2003
1CarbonIBA
05/2003
1Membrane Proteins (Integral Membrane Proteins)IBA
05/2003

Therapy/Procedure

8Therapeutics
02/2020 - 02/2003
1Cell Transplantation
12/2016
1Liver Transplantation
01/2015
1Transplantation
01/2015
1Hematopoietic Stem Cell Transplantation
01/2015
1Aftercare (After-Treatment)
02/2003